Erythromycin-N-Oxide

Product Name Erythromycin-N-Oxide
Alternate Names Erythromycin Impurities, Impurities of Erythromycin
CAT No. CS-CM-00085
CAS No. 992-65-4
Category Impurities
Stock IN-Stock
Mol. Wt. 749.92 g/mol
Mol. For. C₃₇H₆₇NO₁₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Erythromycin
Purity 95%
Therapeutic Antihistamine
Smileys CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)[N+](C)(C)[O-])O)(C)O)C)C)O)(C)O
Canonical Smiles CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)[N+](C)(C)[O-])O)(C)O)C)C)O)(C)O
InchIKey LUIPOVCSQJTWHA-FXYCZVHTSA-N
Inchl InChI=1S/C37H67NO14/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(52-34-28(40)24(38(11,12)46)15-19(3)48-34)21(5)29(22(6)33(43)50-25)51-26-17-36(9,47-13)31(42)23(7)49-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26-,28-,29+,30-,31+,32-,34+,35-,36-,37+/m1/s1
IUPAC (2S,3R,4S,6R)-2-[[(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-2,10-dioxo-oxacyclotetradec-6-yl]oxy]-3-hydroxy-N,N,6-trimethyloxan-4-amine oxide
Controlled No
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Erythromycin-N-Oxide is a derivative of erythromycin, a macrolide antibiotic that is commonly used to treat bacterial infections. Erythromycin-N-Oxide is created by the oxidation of erythromycin, resulting in the addition of an oxygen atom to the molecule. Erythromycin-N-Oxide has been found to have similar antibacterial properties to erythromycin, and is particularly effective against gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aureus. It is also effective against some gram-negative bacteria, including Haemophilus influenzae. The chemical structure of erythromycin-N-oxide allows it to penetrate bacterial cell walls, where it binds to the ribosome and prevents the production of proteins necessary for bacterial growth and replication. This ultimately leads to the death of the bacteria. Erythromycin-N-Oxide is commonly used in the treatment of respiratory tract infections, skin and soft tissue infections, and some sexually transmitted infections. It is available in oral and topical formulations. As with all antibiotics, it is important to use erythromycin-N-Oxide only as prescribed by a healthcare professional, and to complete the full course of treatment to ensure that all bacteria are eliminated. Overuse or misuse of antibiotics can lead to antibiotic resistance, which is a growing global health concern.

Related Compounds

Pseudoerythromycin A Hemiketal | Erythromycin Ethylsuccinate | Erythromycin EP Impurity N | Erythromycin Impurity 12 | Silylated Erythromycin Oxime Ketal | N-demethyl-N-formyl-6-O-methyl-erythromycin A-9-oxime | Erythromycin lactobioate B | Erythromycin Impurity H | Erythromycin EP Impurity E N-Oxide | Erythromycin Impurity M | N-Demethyl-N-Propanoyl Erythromycin | Pseudo Erythromycin A Enol Ether | Erythromycin Ethylsuccinate EP Impurity G | Erythromycin A 6,9-Imino Ether | Erythromycin C | Erythromycin EP Impurity M | Erythromycin Ethyl Fumarate | seco Erythromycin | Erythromycin EP Impurity A | Erythromycin Impurity D | Erythromycin phthalyl ester | Erythromycin Impurity E | Azaerythromycin A 11,12-hydrogen borate | Erythromycin Oxime | Erythromycin propionate | Erythromycin oxime base E-isomer | Erythromycin EP Impurity K | Erythromycin Impurity M | Erythromycin A Enol Ether |

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