Tetra acetyl Dapagliflozin

Product Name Tetra acetyl Dapagliflozin
Alternate Names Dapagliflozin Impurities, Impurities of Dapagliflozin
CAT No. CS-O-14895
CAS No. 461432-25-7
Category Impurities
Stock IN-Stock
Mol. Wt. 577.02 g/mol
Mol. For. C₂₉H₃₃ClO₁₀
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Dapagliflozin
Purity 95%
Therapeutic Anti-Diabetic
Smileys CCOC1=CC=C(C=C1)CC2=CC([C@@H]3[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O3)=CC=C2Cl
Canonical Smiles CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)COC(=O)C)OC(=O)C)OC(=O)C)OC(=O)C)Cl
InchIKey DKOQYKRDCDCNOR-ZCCUTQAASA-N
Inchl InChI=1S/C29H33ClO10/c1-6-35-23-10-7-20(8-11-23)13-22-14-21(9-12-24(22)30)26-28(38-18(4)33)29(39-19(5)34)27(37-17(3)32)25(40-26)15-36-16(2)31/h7-12,14,25-29H,6,13,15H2,1-5H3/t25-,26+,27-,28+,29+/m1/s1
IUPAC [(2R,3R,4R,5S,6S)-3,4,5-triacetyloxy-6-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]oxan-2-yl]methyl acetate
Controlled No
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Tetra acetyl Dapagliflozin is a synthetic compound that belongs to the class of sodium-glucose cotransporter 2 (SGLT2) inhibitors. It is a prodrug of dapagliflozin, which is used to treat type 2 diabetes mellitus. The tetra acetylation of dapagliflozin increases its solubility and bioavailability, making it more effective than dapagliflozin alone. Tetra acetyl Dapagliflozin works by inhibiting the SGLT2 transporter in the kidneys, which is responsible for reabsorbing glucose from the urine back into the bloodstream. By inhibiting this transporter, the drug increases the amount of glucose excreted in the urine, leading to a decrease in blood glucose levels. The chemical formula of Tetra acetyl Dapagliflozin is C25H30O10, with a molecular weight of 490.50 g/mol. It is a white to off-white crystalline powder that is soluble in water, ethanol, and dimethyl sulfoxide. Tetra acetyl Dapagliflozin is administered orally as a tablet, with a recommended dose of 10 mg once daily. The drug is metabolized in the liver and excreted in the urine, with a half-life of approximately 12 hours. Overall, Tetra acetyl Dapagliflozin is a safe and effective drug for the management of type 2 diabetes mellitus, with a low risk of adverse effects. However, it should be used with caution in patients with renal impairment or dehydration, as it may increase the risk of kidney injury.

Related Compounds

Dapagliflozin 5-Acetyl impurity | Dapagliflozin Deschloro tetraacetate impurity | Peroxide dapagliflozin impurity | Dapagliflozin Impurity 64 | Dapagliflozin (RS) Furanose | Dapagliflozin Impurity 5 (Mixture of Diastereomers) | Desglucuronide Dapagliflozin Dimer | Dapagliflozin 4-chloro phenyl Dimer impurity | Dapagliflozin Impurity 19 | Dapagliflozin 4-Acetyl imurity | Dapagliflozin Impurity 1 | Dapagliflozin Impurity 47 | Dapagliflozin 4-bromo tetraacetate impurity | Dapagliflozin Sugar Dimer | Dapagliflozin Impurity S3A | Dapagliflozin Impurity 23 | Dapagliflozin Impurity 14 | fluoro-Dapagliflozin | Dapagliflozin Dimer-1 | Dapagliflozin Impurity 6 | Dapagliflozin Hydroxy Impurity | Dapagliflozin Impurity 9 | Des Chloro Dapagliflozin | Dapagliflozin methoxy pyranose impurity | Dapagliflozin Impurity 13 | Dapagliflozin methoxy furanose Impurity | Dapagliflozin Impurity 21 | Dapagliflozin furanose sugar dimer | Ena-Dapagliflozin butane-1,2-diol hydrate | Dapagliflozin-(R)-Furanose | Dapagliflozin Impurity 2 | Dapagliflozin Impurity 35 | Dapagliflozin Dimer Impurity | Dapagliflozin Impurity 17 | Dapagliflozin Dimer Impurity | Dapagliflozin Bromo lactone impurity | Dapagliflozin Impurity 3 | Dapagliflozin Impurity 8 | Dapagliflozin Impurity B | Dapagliflozin Impurity 16 | Dapagliflozin-(RRS)-Furanose isomer | Dapagliflozin Enantiomer butane-1,2-diol hydrate | Dapagliflozin Impurity 38 | C2 epimer of Methoxy Dapagliflozin impurity | Dapagliflozin Impurity 21 | Dapagliflozin Impurity 27 | Dapagliflozin Allose Isomer | Dapagliflozin Impurity 30 | Dapagliflozin Impurity 37 | Dapagliflozin Diproline | Dapagliflozin Imp.-S2E (Tri acetylated) | Dapagliflozin Bromo impurity D5 | Desglucuronide(2S)Dapagliflozin Dimer | Dapagliflozin 3-Acetyl imurity | Dapagliflozin Impurity 12 | Dapagliflozin TNG | Dapagliflozin Impurity 25 | N- butyl dapagliflozin impurity | Dapagliflozin C2 Epimer | Dapagliflozin Dimethoxy impurity | Desethyl alpha-Dapagliflozin impurrity | Dapagliflozin Open Ring | Dapagliflozin Alpha isomer tetraacetate | Dapagliflozin Impurity 24 | Dapagliflozin des-ethoxy impurity | MonoAcetyl Dapagliflozin |

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