Product Name |
Chlorobutyl ether impurity of Abiraterone |
Alternate Names |
Abiraterone Impurities, Impurities of Abiraterone |
CAT No. |
CS-O-35334
|
CAS No. |
Not Available |
Category |
Impurities |
Stock |
IN-Stock
|
Mol. Wt. |
440.06 g/mol |
Mol. For. |
C₂₈H₃₈ClNO
|
Hazardous |
This is not a Hazardous Compound
|
COA |
View Sample COA
|
MSDS |
View Sample MSDS
|
Parent API |
Abiraterone |
Smileys |
C[C@@]12C(C3=CC=CN=C3)=CC[C@@]1([H])[C@]4([H])CC=C5C[C@@H](OCCCCCl)CC[C@]5(C)[C@@]4([H])CC2
|
Controlled |
No |
Shipping |
Free for purchase above 1000$ |
Delivery |
In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
Return |
Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
Ordering |
Place your order online or by email sales@clearsynth.com |
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Chlorobutyl ether is an impurity found in the drug Abiraterone, a medication used to treat prostate cancer. This impurity is a chlorinated derivative of butyl ether, which is a common solvent used in industrial applications. The presence of chlorobutyl ether in Abiraterone is a cause for concern, as it is classified as a potential human carcinogen by the International Agency for Research on Cancer (IARC).
The chemical structure of chlorobutyl ether is C4H9ClO, and it is a colorless liquid with a boiling point of 115-117°C. It is soluble in most organic solvents but insoluble in water. The primary route of exposure to this impurity is inhalation, as it can evaporate from the medication during handling or administration.
The use of Abiraterone as a cancer treatment involves inhibiting the production of androgens, which are hormones that promote the growth of prostate cancer cells. However, the presence of chlorobutyl ether in this medication raises concerns about the potential for adverse health effects in patients. The U.S. Food and Drug Administration (FDA) has set limits on the amount of chlorobutyl ether that can be present in Abiraterone, and manufacturers are required to test for this impurity during the production process.
In conclusion, the presence of chlorobutyl ether in Abiraterone is a chemical impurity that poses potential health risks to patients. Manufacturers must take precautions to limit the presence of this impurity during the production process, and healthcare professionals must be aware of the risks associated with handling and administering this medication.