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1'-D-cytidine, also known as 1'-deoxy-cytidine, is a modified nucleoside that is used in scientific research and medical applications. It is a derivative of cytidine, a nucleoside composed of the nucleobase cytosine and the sugar ribose. In 1'-D-cytidine, the ribose sugar has been modified by removing the oxygen atom at the 1' position, which changes the chemical properties of the molecule.
1'-D-cytidine is commonly used in studies of RNA and DNA metabolism, as well as in the development of antiviral drugs. As a nucleoside analog, it can be incorporated into growing nucleic acid chains and disrupt the normal structure and function of these molecules. This can be useful in studying the effects of mutations or in designing drugs that target specific viral or cancerous cells.
In terms of chemical properties, 1'-D-cytidine is a white crystalline powder that is soluble in water and other polar solvents. It has a molecular weight of 243.2 g/mol and a melting point of 218-220°C. The modified sugar structure makes it more resistant to enzyme degradation and more stable than cytidine in certain conditions.
Overall, 1'-D-cytidine is a valuable tool in scientific research and drug development, offering unique properties and applications in the study of nucleic acids and their functions.
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