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Ceftazidime EP Impurity B is a chemical compound that is commonly used as an impurity reference standard for Ceftazidime, a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. Ceftazidime EP Impurity B is used to ensure the quality, purity, and potency of Ceftazidime-based medications.
Chemically, Ceftazidime EP Impurity B is identified as (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(1-methyl-1H-tetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. It has a molecular formula of C16H18N10O5S3 and a molecular weight of 554.6 g/mol.
The usage of Ceftazidime EP Impurity B is critical in the pharmaceutical industry as it helps in the determination of impurity levels in Ceftazidime formulations. The impurity can be detected using high-performance liquid chromatography (HPLC) and other analytical techniques. The presence of impurities in Ceftazidime formulations can compromise its efficacy and safety, hence the need for strict quality control measures.
In conclusion, Ceftazidime EP Impurity B is an essential reference standard for the quality control of Ceftazidime-based medications. Its usage in the pharmaceutical industry ensures the safety and efficacy of these medications, ultimately benefiting patients.
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