N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid

Also known as: - Nitrosamine Impurities or nitrosamine impurities of -
Product Name N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid
Alternate Names - Stable Isotopes, Stable Isotopes of -
CAT No. CS-T-94540
CAS No. 30248-47-6 (Unlabelled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 135.13 g/mol
Mol. For. C4HD5N2O3
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API -
Controlled No
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N-Nitroso-L-(azetidine-d5)-2-carboxylic Acid (d5-NO-ACA) is a stable isotopically labeled derivative of N-Nitroso-L-(azetidine-2-carboxylic acid), which is a potent carcinogenic agent. d5-NO-ACA is used as an internal standard for analyzing NO-ACA in biological samples. This compound is used in the study of the mechanism of nitrosation and carcinogenicity of NO-ACA. The labeled compound is useful for quantitative analysis of NO-ACA in biological samples such as urine and blood. NO-ACA is a potent carcinogen that has been shown to induce tumors in animal models. This compound is formed by the reaction of nitrite with the amino acid proline. NO-ACA is believed to be involved in the formation of nitrosamines, which are known to be carcinogenic. The mechanism of action of NO-ACA is not well understood, but it is believed to be involved in the production of DNA adducts and the inhibition of DNA repair mechanisms. The chemical formula of d5-NO-ACA is C5H4D5N3O3. It has a molecular weight of 176.15 g/mol. The compound has a melting point of 203-205°C and a boiling point of 446.5°C. d5-NO-ACA is soluble in water and ethanol. The compound should be stored at -20°C and protected from light. It is important to handle the compound with caution as it is a potential carcinogen.

Related Compounds

C-α-NAC Trimethoprim-d3 | Phenyl-d5-propanolamine | Octahydro-6-(phenylmethyl)-1H-Pyrrolo[3,4-b]pyridine-d4 | C16-Ceramide-13C2,d2 | Methyl 5-Hydroxy-2-benzimidazolecarbamate-d3 | N-t-Boc-1-adamantylamine-d15 | Dienestrol-D8 | a,a-Diphenyl-2-pyridinemethanol Hydrochloride-d5 | Meldrum’s Acid-13C3 | Mixture of (1,3-Dimethylpyrazole-D3 + 1,5-Dimethylpyrazole-D3) | N-​(Dimethylsulfamoyl)​aniline-​d5 | ZK 159222-d4 | K777 Hydrochloride-d8 | Uvinul A Plus-d4 | Digoxigenin-21,23,23-d3 | n-Octyl 4-Hydroxybenzoate-2,3,5,6-D4 | Vitamin K1-[d7] 2,3-Epoxide | N-Nitrosobenzylmethyl-d3-amine | JWH 073 N-butanoic acid-D7 | N-Fmoc-L-serine-13C3,15N | N-Isopropyl-N-methylamine-d7 Hydrochloride | Dihydro Folic Acid-D4 (Technical Grade) | Di-n-dodecyl-d25-dimethylammonium Bromide (mono-n-dodecyl-d25) | Amisometradine-d3 | rac-1,2-Dioctanoyl-3-Chloropropanediol-d5 | Guanosine-13C5 5’-Monophosphate | trans (2,3)-Dihydro Tetrabenazine-d6 (Isobutyl D6) | Salicylic Acid 2-O-b-D-Glucoside-D4 | Des-(Cyclohexa-2,5-dien-1-one) Androsta-(E)-3-oxobut-1-en-1-yl-2,3,4-13C3) | N-Iodoacetyltyramine-d4 | Isopropyl Salicylate-D7 | Sulfaethoxypyridazine-d7 (major) | rac-Hesperetin 7-O-Sulfate Sodium Salt-d3 | Clofarabine-13C1, 15N3 | Diethyl 2-(2-(1,3-Dioxoisoindolin-2-yl-15N)acetyl)succinate-13C4 | Phosphoric Acid Tris(4-​methylphenyl)-d21 Ester | Metamizole-d6 Magnesium Salt Dimer | Triglycidyl Isocyanurate-d15 | Thyroxine Glucuronide-13C6 Disodium Salt | N-Nitrosopendimethalin-d4 | WS-3-13C3 | N-(Phenethyl)pyridinium-d5 Bromide | N-[2-[5-(Acetyloxy)-1H-indol-3-yl]ethyl]acetamide-D6 | Alternariol Monomethyl Ether-d3 | Chenodeoxycholic Acid-d7 (Major) | B-[2-Fluoro-3-(methoxy-d3)phenyl]boronic Acid | S-(5'-Adenosyl)-L-homocysteine-d4 | BETA-METHYLCHOLINE D3 | Abrine-[d3] | DL-DOPA-2,5,6-d6 | N-Acetylneuraminic Acid Methyl Ester-d5 | Harman-D4 | Dehydro Glycopyrrolate Iodide-D3 (Mixture of Diastereomers) | Ramipril Isopropyl-d3 Ester | p-Anisaldehyde Propylene Glycol Acetal-d3 | Trimellitic Acid -13C3 | Sodium 1H,1H,2H,2H-Perfluorohexane Sulfonate-13C2 | Itaconic Acid-13C5,d4 | Androsta-1,4-dien-3,17-dione-2,3,4-13C3 | Ethylene Gycol Monomyristate-d4 | a-Methyl-trans-cinnamaldehyde-d5 | Simazine-13C5 | Sulfo-NHS-LC-Biotin-D10 | Oxybenzone-(phenyl-13C6) | Cannflavin A-d3 | S-(2-Hydroxyethyl)glutathione-d4 Hydrochloride | Pentanoic-3,3,4,4,5,5,5-d7 acid, ethyl ester | Secnidazole-d3 | Chloroacetic Acid-d2 | p-Tyramine-d4 Hydrochloride (ethyl-D4) |

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