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(S)-Praziquantel-d11 is a deuterium-labeled form of the drug praziquantel, which is a broad-spectrum anthelmintic medication used to treat parasitic worm infections in both humans and animals. The drug is highly effective against a variety of trematode and cestode parasites that infect the human body, including schistosomiasis, a major neglected tropical disease.
The chemical formula of (S)-Praziquantel-d11 is C19H16D11ClN2O2, with a molecular weight of 330.90 g/mol. The compound is a white to off-white powder that is stable under normal storage conditions.
(S)-Praziquantel-d11 works by disrupting the calcium balance in the parasites’ muscle cells, leading to paralysis and subsequent death of the worms. The drug is rapidly absorbed into the bloodstream and distributed throughout the body, where it can target the parasites in various tissues and organs.
(S)-Praziquantel-d11 is primarily used in research studies to investigate the pharmacokinetics and metabolism of praziquantel in vivo. Its deuterium labeling allows for more accurate quantification of drug levels in biological samples using mass spectrometry techniques.
Overall, (S)-Praziquantel-d11 is a valuable tool for understanding the mechanisms of action and efficacy of praziquantel, and may ultimately contribute to the development of new treatments for parasitic worm infections.
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