(±)-Ibuprofen-d4 (propionic -2,3,3,3-d4)

(±)-Ibuprofen-d4 (propionic-2,3,3,3-d4) is a deuterated form of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) commonly used to treat pain, fever, and inflammation. The d4 designation refers to the replacement of four hydrogen atoms with deuterium isotopes, which makes it useful in pharmaceutical research and analysis. The chemical formula of (±)-Ibuprofen-d4 is C13H16D4O2, and it has a molecular weight of 224.33 g/mol. The deuterated form of ibuprofen is a white crystalline powder that is soluble in ethanol, methanol, and acetone. In terms of usage, (±)-Ibuprofen-d4 is primarily used in drug metabolism studies, pharmacokinetic studies, and bioavailability studies. It is also used in the development of analytical methods for identifying and quantifying ibuprofen in biological samples, such as blood, urine, and plasma. The deuterated form of ibuprofen is advantageous in these studies because it allows researchers to distinguish between the metabolites of ibuprofen and other drugs that may be present in the sample. Additionally, the use of (±)-Ibuprofen-d4 reduces the risk of false positives and improves the accuracy and reliability of the results. In summary, (±)-Ibuprofen-d4 is a deuterated form of ibuprofen that is commonly used in pharmaceutical research and analysis. Its chemical properties make it useful in drug metabolism studies, pharmacokinetic studies, and bioavailability studies.