[1'-D]2'-deoxyadenosine monohydrate

[1'-D]2'-deoxyadenosine monohydrate is a nucleoside analog that is widely used in biochemical research for studying DNA replication, repair, and modification. It is a modified form of the natural nucleoside adenosine, in which the hydroxyl group at the 2' position of the sugar ring is replaced with a hydrogen atom, and a deuterium atom is substituted at the 1' position of the ribose ring. This modification makes [1'-D]2'-deoxyadenosine monohydrate resistant to enzymatic degradation, allowing it to be incorporated into DNA molecules and traced through various cellular processes. The chemical formula of [1'-D]2'-deoxyadenosine monohydrate is C10H13D2N5O3•H2O, and its molecular weight is 289.3 g/mol. It is a white crystalline powder that is soluble in water, but insoluble in organic solvents. The compound is stable under normal laboratory conditions, but should be kept away from strong oxidizing agents and light. In addition to its research applications, [1'-D]2'-deoxyadenosine monohydrate has potential therapeutic uses in cancer treatment, as it can interfere with DNA synthesis and induce cell death in cancer cells. However, more studies are needed to determine its safety and efficacy in humans. Overall, [1'-D]2'-deoxyadenosine monohydrate is a valuable tool for understanding DNA biology and has promising therapeutic potential.