[1'-D]2'-deoxyguanosine monohydrate

[1'-D]2'-deoxyguanosine monohydrate is a nucleoside analogue that is commonly used in molecular biology research. It is a modified form of guanosine, one of the four building blocks of DNA. The "D" in the name refers to the stereochemistry of the molecule, indicating that it is in the naturally occurring configuration. This molecule is used in a variety of applications, such as in DNA sequencing and as a substrate for DNA polymerase in PCR reactions. It can also be used in studies of DNA damage and repair, as it can be incorporated into DNA and then analyzed to determine the effects of various treatments on the DNA. The chemical structure of [1'-D]2'-deoxyguanosine monohydrate includes a deoxyribose sugar, a nitrogenous base (guanine), and a phosphate group. The molecule is a white to off-white powder that is soluble in water and has a melting point of around 230-235°C. It is important to note that [1'-D]2'-deoxyguanosine monohydrate is considered a hazardous substance and should be handled with appropriate precautions. It can cause skin and eye irritation, and prolonged exposure may lead to more serious health effects. Proper protective equipment and handling procedures should be used when working with this molecule.