[13C6]-Alogliptin

[13C6]-Alogliptin is a synthetic compound that is used in the treatment of type 2 diabetes. It belongs to a class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors, which work by increasing insulin secretion and lowering blood sugar levels. [13C6]-Alogliptin is a stable isotope-labeled version of alogliptin, meaning that six carbon atoms in the drug molecule are replaced with the heavier isotope carbon-13. [13C6]-Alogliptin is administered orally in the form of tablets, usually once a day. It is rapidly absorbed into the bloodstream and reaches peak plasma concentration within two hours of ingestion. The drug is metabolized in the liver and excreted in the urine. Chemically, [13C6]-Alogliptin is a white to off-white powder with a molecular formula of C18H17N5O2. It has a molecular weight of 339.4 g/mol and a melting point of 194-195°C. The compound is stable under normal storage conditions and is not affected by light or moisture. [13C6]-Alogliptin is typically used as a second-line treatment for patients with type 2 diabetes who have not achieved adequate glycemic control with diet and exercise alone. It can be used alone or in combination with other antidiabetic drugs such as metformin or insulin. The drug is generally safe and well-tolerated, with few reported side effects. However, like all medications, it may interact with other drugs and should be used with caution in patients with certain medical conditions such as liver or kidney disease.