(1R,2S,5R)-(-)-Menthol-d4

(1R,2S,5R)-(-)-Menthol-d4 is a deuterated form of (-)-menthol, which is a naturally occurring organic compound found in peppermint oil. The deuterium atoms in this compound are used for spectroscopic analysis, especially in nuclear magnetic resonance (NMR) spectroscopy. (-)-Menthol is known for its cooling and soothing effects on the skin and is widely used in the pharmaceutical, cosmetic, and food industries. It is used in topical analgesics, cough and cold medications, and as a flavoring agent in chewing gum, toothpaste, and other products. The chemical formula of (1R,2S,5R)-(-)-Menthol-d4 is C10H17DO, and it has a molecular weight of 153.28 g/mol. It is a colorless, crystalline solid with a characteristic minty odor. It is soluble in alcohol, ether, and chloroform, but insoluble in water. The stereochemistry of this compound is important because it affects its biological activity. The (1R,2S,5R) stereochemistry is responsible for the cooling and analgesic effects of (-)-menthol. It acts on the TRPM8 receptor, which is responsible for sensing cold temperatures and pain. In conclusion, (1R,2S,5R)-(-)-Menthol-d4 is a useful tool for spectroscopic analysis of (-)-menthol and its derivatives. Its stereochemistry is important for its biological activity, and it is widely used in various industries for its cooling and soothing effects.