(1R,4S,4aR,9aS)-rel-1,4,4a,9a-Tetrahydro-4a-methyl-1,4-methanoanthracene-9,10-dione-d8
| Product Name | (1R,4S,4aR,9aS)-rel-1,4,4a,9a-Tetrahydro-4a-methyl-1,4-methanoanthracene-9,10-dione-d8 |
|---|---|
| Alternate Names | Anthracene Stable Isotopes, Stable Isotopes of Anthracene |
| CAT No. | CS-T-86647 |
| CAS No. | 1329799-73-6 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Anthracene |
| Smileys | O=C1C2=C(C([2H])=C([2H])C([2H])=C2[2H])C([C@@]3([2H])[C@@H]4C=C[C@@H](C4)[C@@]13C([2H])([2H])[2H])=O |
| Canonical Smiles | CC12C3CC(C1C(=O)C4=CC=CC=C4C2=O)C=C3 |
| InchIKey | NELNWZJOZOSDFH-ROKNWGGVSA-N |
| Inchl | InChI=1S/C16H14O2/c1-16-10-7-6-9(8-10)13(16)14(17)11-4-2-3-5-12(11)15(16)18/h2-7,9-10,13H,8H2,1H3/t9-,10+,13+,16+/m0/s1/i1D3,2D,3D,4D,5D,13D |
| IUPAC | (1R,2S,11R,12S)-2,5,6,7,8-pentadeuterio-11-(trideuteriomethyl)tetracyclo[10.2.1.02,11.04,9]pentadeca-4,6,8,13-tetraene-3,10-dione |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
(1R,4S,4aR,9aS)-rel-1,4,4a,9a-Tetrahydro-4a-methyl-1,4-methanoanthracene-9,10-dione-d8 is a deuterated form of a chemical compound that has numerous applications in various fields, including pharmaceutical, research, and chemical industries. This chemical compound is also known as camptothecin, which is a naturally occurring alkaloid that is extracted from the bark and stem of the Camptotheca acuminata tree.
Camptothecin and its derivatives have been extensively studied for their antitumor properties. It has been found to inhibit the activity of the enzyme topoisomerase I, which is essential for DNA replication and transcription. This inhibition leads to the formation of stable ternary complexes between topoisomerase I, DNA, and camptothecin, resulting in DNA damage and apoptosis of cancer cells.
The deuterated form of camptothecin, (1R,4S,4aR,9aS)-rel-1,4,4a,9a-Tetrahydro-4a-methyl-1,4-methanoanthracene-9,10-dione-d8, is used in research to study the pharmacokinetics and metabolism of camptothecin and its derivatives. The deuterium-labeled compound allows for more accurate analysis of the absorption, distribution, metabolism, and excretion of camptothecin in animal and human studies.
In summary, (1R,4S,4aR,9aS)-rel-1,4,4a,9a-Tetrahydro-4a-methyl-1,4-methanoanthracene-9,10-dione-d8 is a valuable tool for studying the antitumor properties and pharmacokinetics of camptothecin and its derivatives, providing important insights into the development of novel cancer therapies.
Get an Instant Quote
Related Compounds
Acenaphth[1,2-b]anthracene-d14 | Anthracene 13C6 | Acenaphth[1,2-a]anthracene-d14 | Dibenz[a,h]anthracene-d14 |