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(1S,3?R)-Solifenacin-d7 HCl (quinuclidinyl-d7) is a deuterated form of solifenacin, which is a medication used to treat overactive bladder symptoms such as frequent urination and urgency. The deuterated form is used in research and development as a stable isotope-labeled internal standard for the quantification of solifenacin in biological matrices using mass spectrometry.
Solifenacin belongs to the class of drugs known as antimuscarinics, which work by blocking the activity of acetylcholine, a neurotransmitter that is responsible for muscle contractions in the bladder. By doing so, solifenacin reduces bladder contractions, increases bladder capacity, and decreases the urge to urinate.
(1S,3?R)-Solifenacin-d7 HCl (quinuclidinyl-d7) has the same chemical formula as solifenacin, C23H28D7ClN2O4, but with seven deuterium atoms incorporated into its structure. The deuterium labeling provides a unique molecular signature that allows for accurate measurement of solifenacin levels in biological samples.
In summary, (1S,3?R)-Solifenacin-d7 HCl (quinuclidinyl-d7) is a stable isotope-labeled internal standard used in research and development to accurately measure solifenacin levels in biological matrices using mass spectrometry. Its usage helps in the development of new drugs and in understanding the pharmacokinetic profile of solifenacin.
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