2-Amino-3-methyl-3H-imidazo[4,5-f]quinoxaline-d3

2-Amino-3-methyl-3H-imidazo[4,5-f]quinoxaline-d3 is a deuterated version of 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoxaline (IQ), a heterocyclic compound that belongs to the imidazoquinoxaline family. IQ is a potent mutagen and a known carcinogen, commonly found in cooked meat and fish products. It has been linked to the development of various cancers, including colon, liver, and lung cancer. 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoxaline-d3 is a stable isotopic labeled form of IQ that is often used in scientific research to study the metabolic pathways and toxicity of IQ in biological systems. Its chemical formula is C9H4D3N3, with a molecular weight of 172.21 g/mol. It is a white to off-white powder that is soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide. The primary use of 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoxaline-d3 is in the field of analytical chemistry, where it is used as a reference standard for the quantification of IQ in food samples using analytical techniques such as gas chromatography-mass spectrometry (GC-MS). It is also used in pharmacokinetic studies to track the absorption, distribution, metabolism, and excretion of IQ in animal and human models. Its deuterated nature allows for easier differentiation between endogenous and exogenous sources of IQ in biological samples. In conclusion, 2-Amino-3-methyl-3H-imidazo[4,5-f]quinoxaline-d3 is an important analytical tool for the study of IQ in various biological systems. Its stable isotopic labeling allows for accurate quantification and tracking of the compound in complex matrices, leading to a better understanding of its potential health effects.