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(2RS)-Valganciclovir-d8 HCl (L-valine-d8) is a deuterated form of Valganciclovir, which is an antiviral medication used to treat cytomegalovirus infections in immunocompromised patients. This medication belongs to the class of drugs known as guanine nucleoside analogs, which work by inhibiting viral DNA replication.
The deuterated form of this medication, (2RS)-Valganciclovir-d8 HCl (L-valine-d8), is used for research purposes as a stable isotope-labeled internal standard for quantitative analysis of Valganciclovir in biological matrices. It is also used in pharmacokinetic studies to determine the bioavailability, metabolism, and elimination of the drug in the body.
Chemical information about this medication includes its chemical formula, which is C14H18D8ClN6O5, and its molecular weight, which is 392.84 g/mol. The deuterated form of this medication has eight deuterium atoms in place of hydrogen atoms, which makes it more stable and less prone to degradation in biological matrices.
Overall, (2RS)-Valganciclovir-d8 HCl (L-valine-d8) is an important tool for researchers studying the pharmacokinetics of Valganciclovir, as well as for those developing new antiviral drugs in the same class. Its stable isotope labeling allows for accurate and precise analysis of the drug in biological samples, which is crucial for understanding its efficacy and safety in patients.
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