(2S,2′S)-Ethambutol-d10 (1,1,1′,1′,2,2′-d6; ethylene-d4)

(2S,2?S)-Ethambutol-d10 (1,1,1?,1?,2,2?-d6; ethylene-d4) is a deuterated form of Ethambutol, which is a medication used to treat tuberculosis. It is a chiral molecule with two stereocenters, denoted by the S and R labels. The deuterated form of the drug contains ten deuterium atoms, which replace ten hydrogen atoms in the non-deuterated compound. This modification can be useful in pharmacokinetic studies to track the drug’s metabolism and distribution in the body. Ethambutol works by inhibiting the synthesis of mycobacterial cell walls, which are essential for the survival of tuberculosis bacteria. The drug is primarily used in combination with other medications to treat active tuberculosis infections. However, it may also be used as a prophylactic treatment for individuals at high risk of developing tuberculosis. The chemical structure of Ethambutol-d10 includes a benzene ring, a secondary amine, and an ethylene chain. The deuterium atoms in the molecule are located on the benzene ring, the amine group, and the ethylene chain. The molecular weight of the deuterated form of the drug is higher than the non-deuterated compound, which may affect its pharmacological properties. Overall, Ethambutol-d10 is a useful tool for studying the pharmacokinetics and metabolic pathways of Ethambutol in the body.