[3'-D]2'-deoxyguanosine monohydrate

[3'-D]2'-deoxyguanosine monohydrate is a modified form of the natural nucleoside 2'-deoxyguanosine. It has a deuterium atom at the 3' position of the ribose sugar. This modification allows for easier tracking and analysis of DNA and RNA molecules in biological systems. The usage of [3'-D]2'-deoxyguanosine monohydrate is primarily in research and diagnostic applications. It is commonly used as a tracer in studies of DNA replication, transcription, and repair. The deuterium labeling allows for the monitoring of the fate and movement of DNA and RNA molecules in biological systems. This information can be used to better understand the mechanisms of genetic diseases and to develop new diagnostic and therapeutic interventions. Chemically, [3'-D]2'-deoxyguanosine monohydrate is a white crystalline powder. It has a molecular formula of C10H13N5O4 and a molecular weight of 267.24 g/mol. The monohydrate form contains one molecule of water per molecule of nucleoside. It is soluble in water and ethanol, but insoluble in ether and chloroform. In summary, [3'-D]2'-deoxyguanosine monohydrate is a valuable tool for studying DNA and RNA molecules in biological systems. Its deuterium labeling allows for easy tracking and analysis, providing insights into the mechanisms of genetic diseases and potential treatments.