3-Methyl-d3-1,1-diphenylurea

3-Methyl-d3-1,1-diphenylurea, also known as MDPU, is a stable isotope-labeled urea derivative that is commonly used as an internal standard in mass spectrometry applications. It is a white crystalline powder that has a molecular weight of 270.36 g/mol. MDPU is a deuterated analogue of diphenylurea, which is a herbicide that inhibits photosynthesis in plants. MDPU is used as an internal standard in mass spectrometry analysis to accurately quantify the concentration of target analytes in complex biological samples. It is commonly used in the analysis of small molecules, such as drugs, metabolites, and biomarkers, in various biological matrices, including blood, urine, and tissue samples. MDPU is preferred over other internal standards due to its stable isotopic composition, which allows for accurate and precise quantification of target analytes. In terms of its chemical properties, MDPU is a derivative of urea, which contains two phenyl groups and one methyl group attached to the nitrogen atoms. The deuterium atoms in MDPU replace the hydrogen atoms in the non-aromatic part of the molecule. MDPU is stable under normal conditions and is not reactive with other compounds. It has a melting point of 207-209°C and is soluble in common organic solvents, such as methanol, ethanol, and acetone. In conclusion, 3-Methyl-d3-1,1-diphenylurea is an important internal standard that is widely used in mass spectrometry analysis. Its stable isotopic composition and chemical stability make it an ideal reference compound for accurate and precise quantification of target analytes in complex biological samples.