[8-D]2'-deoxyadenosine monohydrate

[8-D]2'-deoxyadenosine monohydrate is a modified form of 2'-deoxyadenosine, which is a nucleoside component of DNA. This modified form has a deuterium atom substituted at the 8-carbon position of the adenine ring, making it useful for research into DNA replication and repair processes. The chemical formula for [8-D]2'-deoxyadenosine monohydrate is C10H12D2N5O3•H2O, and its molecular weight is 274.25 g/mol. It is a white to off-white crystalline powder that is soluble in water and has a melting point of 239-241°C. In terms of usage, [8-D]2'-deoxyadenosine monohydrate is primarily used in studies focused on DNA synthesis and repair mechanisms. Its unique chemical structure allows researchers to track the movement of DNA and monitor the action of enzymes involved in DNA repair. It has also been used in studies of cancer cells, as the abnormal replication of DNA is a hallmark of cancer cells. While [8-D]2'-deoxyadenosine monohydrate is generally considered to be safe, it should be handled with care and appropriate protective measures should be taken when working with it in a laboratory setting. It is important to note that this compound is intended for research use only and is not intended for human consumption or therapeutic use.