(S)-Cinacalcet-D3

Product Name (S)-Cinacalcet-D3
Alternate Names Cinacalcet Stable Isotopes, Stable Isotopes of Cinacalcet
CAT No. CS-O-38751
CAS No. 694495-47-1 (unlabelled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 360.43 g/mol
Mol. For. C22H19D3F3N
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Cinacalcet
Controlled No
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What is the usage and chemical information of (S)-Cinacalcet-D3 ?


(S)-Cinacalcet-D3 is a deuterated analog of the drug Cinacalcet, which is used for the treatment of hyperparathyroidism and hypercalcemia in patients with chronic kidney disease. The deuterated form of the drug, (S)-Cinacalcet-D3, is used in research and development to study the pharmacokinetics and metabolism of Cinacalcet. The mechanism of action of Cinacalcet and its deuterated analog involves binding to the calcium-sensing receptor (CaSR) on the parathyroid gland, which suppresses the secretion of parathyroid hormone (PTH). This leads to a decrease in the levels of calcium in the blood, which is beneficial for patients with hyperparathyroidism and hypercalcemia. The chemical formula of (S)-Cinacalcet-D3 is C22H22D3F3N, and it has a molecular weight of 351.42 g/mol. The drug is administered orally, with a recommended dosage of 30-180 mg per day. (S)-Cinacalcet-D3 is metabolized by the liver, primarily through the cytochrome P450 system. The drug has a half-life of approximately 30 hours and is excreted in the urine and feces. (S)-Cinacalcet-D3 is an important tool in the study of the pharmacokinetics and metabolism of Cinacalcet. Its deuterated form allows for more accurate measurements of the drug's distribution, elimination, and bioavailability in the body.

Related Compounds

Cinacalcet-d4 Hydrochloride | Cinacalcet D4 | Rac-Cinacalcet D3 Hydrochloride | Cinacalcet D3 Hydrochloride | Cinacalcet D3 |

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