(S)-Cinacalcet-D3 Hydrochloride

Product Name (S)-Cinacalcet-D3 Hydrochloride
Alternate Names Cinacalcet Stable Isotopes, Stable Isotopes of Cinacalcet
CAT No. CS-F-00166
CAS No. 1217809-88-5 (unlabelled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 396.89 g/mol
Mol. For. C22H20D3ClF3N
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Cinacalcet
Smileys FC(C1=CC(CCCN[C@H](C2=C3C=CC=CC3=CC=C2)C([2H])([2H])[2H])=CC=C1)(F)F.[H]Cl
Canonical Smiles CC(C1=CC=CC2=CC=CC=C21)NCCCC3=CC(=CC=C3)C(F)(F)F.Cl
InchIKey QANQWUQOEJZMLL-NTISSMGPSA-N
Inchl InChI=1S/C22H22F3N.ClH/c1-16(20-13-5-10-18-9-2-3-12-21(18)20)26-14-6-8-17-7-4-11-19(15-17)22(23,24)25;/h2-5,7,9-13,15-16,26H,6,8,14H2,1H3;1H/t16-;/m0./s1
IUPAC N-[(1S)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine;hydrochloride
Controlled No
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What is the usage and chemical information of (S)-Cinacalcet-D3 Hydrochloride ?


(S)-Cinacalcet-D3 Hydrochloride is a medication used to treat secondary hyperthyroidism in patients with chronic kidney disease and parathyroid carcinoma. This medication is a derivative of Cinacalcet Hydrochloride, with deuterium isotopes added to the molecular structure. It is a chiral drug, meaning that it has two enantiomers, or mirror-image molecules, with different biological activities. The (S)-enantiomer is the active form, while the (R)-enantiomer is inactive. The mechanism of action of (S)-Cinacalcet-D3 Hydrochloride involves binding to the calcium-sensing receptors on the parathyroid gland, which reduces the secretion of parathyroid hormone. This leads to a decrease in serum calcium and phosphate levels, which helps to prevent bone disease and cardiovascular complications associated with chronic kidney disease. Chemically, (S)-Cinacalcet-D3 Hydrochloride has a molecular formula of C22H21D3ClFNO2 and a molecular weight of 390.9 g/mol. It is a white to off-white crystalline powder that is soluble in water and ethanol. The recommended dose of this medication varies depending on the patient's condition and response to treatment, and it should be taken as directed by a healthcare professional. Overall, (S)-Cinacalcet-D3 Hydrochloride is an important medication in the management of secondary hyperparathyroidism in patients with chronic kidney disease and parathyroid carcinoma. Its unique molecular structure and mechanism of action make it an effective and valuable treatment option for these conditions.

Related Compounds

Cinacalcet D3 Hydrochloride | Cinacalcet D4 | Cinacalcet D3 | Cinacalcet-d4 Hydrochloride | Rac-Cinacalcet D3 Hydrochloride |

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