12-Ethyl Rapamycin
| Product Name | 12-Ethyl Rapamycin |
|---|---|
| Alternate Names | Rapamycin Impurities, Impurities of Rapamycin |
| CAT No. | CS-P-08464 |
| CAS No. | 1290606-20-0 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 928.21 g/mol |
| Mol. For. | C52H81NO13 |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Rapamycin |
| Smileys | O=C(C(N1CCCC[C@H]1C(O[C@H]([C@H](C)C[C@@H]2CC[C@@H](O)[C@H](OC)C2)CC([C@H](C)/C=C(C)/[C@@H](O)[C@H]3OC)=O)=O)=O)[C@@](O4)(O)[C@H](CC)CC[C@H]4C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C3=O |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
12-Ethyl Rapamycin is a chemical compound that is derived from the natural product Rapamycin, which is produced by a bacterium known as Streptomyces hygroscopicus. It is a highly potent immunosuppressive drug that has been used to prevent organ transplant rejection and to treat autoimmune diseases like rheumatoid arthritis and psoriasis. 12-Ethyl Rapamycin works by inhibiting the activation of T-cells, which are responsible for the body's immune response. This inhibition prevents the immune system from attacking transplanted organs or attacking the body's own tissues in autoimmune diseases.
Chemically, 12-Ethyl Rapamycin is a macrolide lactone that has a molecular weight of 958.22 g/mol. It has a complex structure that contains a large ring structure and a unique side chain containing an ethyl group. This structure is responsible for its potent immunosuppressive properties.
12-Ethyl Rapamycin is administered orally or intravenously and has a long half-life of approximately 62 hours. It is metabolized by the liver and excreted in the feces and urine. However, it has potential side effects, such as an increased risk of infections, lymphoma, and skin cancer. 12-Ethyl Rapamycin is a highly potent and effective immunosuppressive drug that has changed the field of organ transplantation and autoimmune disease treatment.
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Related Compounds
Rapamycin 31,42-Bis(2,2,5-trimethyl-1,3-dioxane-5-carboxylate) | Rapamycin Impurity 12 | Rapamycin Impurity 5 (Seco Rapamycin) | Secorapamycin Na salt | Rapamycin Impurity 4 (Sirolimus-31,42-Diester Impurity) | Rapamycin Impurity 1 | Rapamycin Dialdehyde |