2-(Cyclopropylmethoxy-d4)-acetic Acid

2-(Cyclopropylmethoxy-d4)-acetic acid is a deuterated derivative of 2-(cyclopropylmethoxy)acetic acid, a carboxylic acid containing a cyclopropylmethoxy moiety. The compound is labeled with four deuterium atoms, which are stable isotopes of hydrogen that are often used in drug metabolism studies. The primary use of 2-(Cyclopropylmethoxy-d4)-acetic acid is in pharmacokinetic studies, which are used to understand how drugs are absorbed, distributed, metabolized, and excreted in the body. The labeled compound is used as a tracer to monitor the fate of the drug in the body, allowing researchers to determine the pharmacokinetic parameters of the drug. In addition to its use in pharmacokinetic studies, 2-(Cyclopropylmethoxy-d4)-acetic acid can also be used in the synthesis of other labeled compounds. The cyclopropylmethoxy group can be modified to introduce other functional groups that are useful in drug discovery and development. From a chemical standpoint, 2-(Cyclopropylmethoxy-d4)-acetic acid is a white crystalline solid with a molecular formula of C6H7D4O3. It has a melting point of 98-101°C and a boiling point of 295-297°C. The compound is soluble in water and ethanol, but insoluble in most organic solvents. Overall, 2-(Cyclopropylmethoxy-d4)-acetic acid is a useful compound for drug metabolism and pharmacokinetic studies, as well as for the synthesis of other labeled compounds. Its stable isotopic labeling makes it a valuable tool for understanding the fate of drugs in the body and for developing new drugs with improved pharmacokinetic properties.