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2-Fluoro Safinamide is a promising drug candidate that has shown potential in treating Parkinson’s disease. It is a selective and reversible inhibitor of monoamine oxidase-B (MAO-B) and also acts as a modulator of dopamine release. The drug has been found to be effective in reducing the symptoms of Parkinson’s disease, such as tremors, rigidity, and bradykinesia.
2-Fluoro Safinamide belongs to the class of compounds known as phenylpropylamines. It is a derivative of Safinamide, which was approved by the FDA in 2017 for the treatment of Parkinson’s disease. The addition of a fluorine atom to the molecule enhances its potency and selectivity towards MAO-B.
The chemical formula of 2-Fluoro Safinamide is C15H14FN3O2. It has a molecular weight of 289.29 g/mol. The drug is administered orally in the form of tablets. The recommended daily dose is 50 mg, which can be increased to 100 mg if necessary.
The safety and efficacy of 2-Fluoro Safinamide have been evaluated in clinical trials. The drug has been found to be generally well-tolerated, with mild to moderate side effects such as nausea, headache, and insomnia. However, it may interact with other drugs that affect the metabolism of dopamine, such as levodopa and dopamine agonists.
In conclusion, 2-Fluoro Safinamide is a promising drug candidate for the treatment of Parkinson’s disease. Its unique mechanism of action and enhanced potency make it a valuable addition to the existing therapies for this debilitating condition.
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