2’-Oxo Ifosfamide-d4

2'-Oxo Ifosfamide-d4 is a stable isotope-labeled derivative of 2'-Oxo Ifosfamide, a chemotherapeutic agent used in the treatment of various types of cancer. It is a prodrug that is converted into the active metabolite, ifosfamide mustard, in the liver and cancer cells. The incorporation of deuterium atoms at specific positions in the molecular structure of 2'-Oxo Ifosfamide-d4 allows for more precise analysis of drug metabolism and pharmacokinetics. The chemical formula of 2'-Oxo Ifosfamide-d4 is C7H9D4Cl2N2O3P, and its molecular weight is 255.09 g/mol. It is available in both powder and solution forms, with a purity level of at least 98%. The recommended storage temperature for this compound is -20°C. In terms of usage, 2'-Oxo Ifosfamide-d4 is primarily used in pharmacokinetic studies to determine the absorption, distribution, metabolism, and excretion of 2'-Oxo Ifosfamide in the body. It is also used in drug-drug interaction studies and bioanalytical assays. The stable isotope-labeled compound is administered to patients, and its concentration in blood, plasma, urine, or other bodily fluids is measured over time using mass spectrometry. Overall, 2'-Oxo Ifosfamide-d4 is a valuable tool in cancer research and drug development, providing researchers with a better understanding of the pharmacokinetics and metabolism of 2'-Oxo Ifosfamide and its potential interactions with other drugs.