2-Desethoxy-2-hydroxy-2H-2-ethyl Candesartan Cilexetil-d5
| Product Name | 2-Desethoxy-2-hydroxy-2H-2-ethyl Candesartan Cilexetil-d5 |
|---|---|
| Alternate Names | Candesartan Stable Isotopes, Stable Isotopes of Candesartan |
| CAT No. | CS-T-73309 |
| CAS No. | 1246820-36-9 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Candesartan |
| Smileys | CCN1N=C(N=N1)C2=CC=CC=C2C3=CC=C(C=C3)CN4C5=C(C=CC=C5NC4=O)C(=O)OC(C)OC(=O)OC6CCCCC6 |
| Canonical Smiles | CCN1N=C(N=N1)C2=CC=CC=C2C3=CC=C(C=C3)CN4C5=C(C=CC=C5NC4=O)C(=O)OC(C)OC(=O)OC6CCCCC6 |
| InchIKey | KORFUGQWQJEFIY-WNWXXORZSA-N |
| Inchl | InChI=1S/C33H34N6O6/c1-3-39-36-30(35-37-39)26-13-8-7-12-25(26)23-18-16-22(17-19-23)20-38-29-27(14-9-15-28(29)34-32(38)41)31(40)43-21(2)44-33(42)45-24-10-5-4-6-11-24/h7-9,12-19,21,24H,3-6,10-11,20H2,1-2H3,(H,34,41)/i1D3,3D2 |
| IUPAC | 1-cyclohexyloxycarbonyloxyethyl 2-oxo-3-[[4-[2-[2-(1,1,2,2,2-pentadeuterioethyl)tetrazol-5-yl]phenyl]phenyl]methyl]-1H-benzimidazole-4-carboxylate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
2-Desethoxy-2-hydroxy-2H-2-ethyl Candesartan Cilexetil-d5, also known as Candesartan Cilexetil-d5, is a deuterated analog of the angiotensin II receptor blocker Candesartan Cilexetil. It is primarily used for the treatment of high blood pressure, which is a major risk factor for heart disease, stroke, and kidney failure. Candesartan Cilexetil-d5 works by blocking the action of angiotensin II, a hormone that causes blood vessels to constrict, thereby reducing blood pressure.
Chemically, Candesartan Cilexetil-d5 is a prodrug that is rapidly converted into its active form, Candesartan, in the body. This conversion occurs via hydrolysis of the ethyl ester group present in the prodrug. The deuterated form of Candesartan Cilexetil-d5 is used for pharmacokinetic studies, where the labeled deuterium atoms are used to track the drug's metabolism and distribution in the body.
Candesartan Cilexetil-d5 is administered orally as a tablet and is available in various strengths. Its pharmacokinetics are similar to those of the non-deuterated form of the drug. The drug is generally well-tolerated, with few side effects reported. The most common side effects include dizziness, headache, and fatigue.
In conclusion, 2-Desethoxy-2-hydroxy-2H-2-ethyl Candesartan Cilexetil-d5 is a deuterated analog of the popular antihypertensive medication Candesartan Cilexetil. It is used primarily for pharmacokinetic studies and is effective in lowering blood pressure. The drug's chemical structure and mechanism of action make it a valuable tool in the treatment of hypertension and its associated complications.
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Related Compounds
Candesartan-d5 | Candesartan Cilexetil D11 | Candesartan D4 | Candesartan-d5 Methyl Ester |