2-Methylcitric Acid-d3
| Product Name | 2-Methylcitric Acid-d3 |
|---|---|
| CAT No. | CS-T-79926 |
| CAS No. | 146764-58-1 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Smileys | CC(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| Canonical Smiles | CC(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| InchIKey | YNOXCRMFGMSKIJ-FIBGUPNXSA-N |
| Inchl | InChI=1S/C7H10O7/c1-3(5(10)11)7(14,6(12)13)2-4(8)9/h3,14H,2H2,1H3,(H,8,9)(H,10,11)(H,12,13)/i1D3 |
| IUPAC | 4,4,4-trideuterio-2-hydroxybutane-1,2,3-tricarboxylic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
2-Methylcitric Acid-d3 is a deuterated form of 2-methylcitric acid, which is an important intermediate in the metabolism of propionic acid. It is a tricarboxylic acid with a molecular formula of C7H7D3O7 and a molecular weight of 211.15 g/mol. The deuterated form is used in biochemical research as a stable isotope-labeled internal standard for the quantification of 2-methylcitric acid in biological samples.
In the human body, 2-methylcitric acid is produced as a result of the breakdown of certain amino acids and fatty acids. Elevated levels of 2-methylcitric acid in the blood and urine are associated with a rare genetic disorder called propionic acidemia. This condition is characterized by the inability to break down certain amino acids and fatty acids, leading to the accumulation of toxic levels of propionic acid and 2-methylcitric acid in the body.
2-Methylcitric Acid-d3 is commonly used in mass spectrometry-based methods for the quantitative analysis of 2-methylcitric acid in biological samples. It is also used as a reference material in the development and validation of analytical methods for the detection and quantification of propionic acidemia. Its stable isotope-labeled structure allows for accurate quantification of 2-methylcitric acid in complex biological matrices, improving the sensitivity and specificity of the analytical method.
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