3-Methyl-L-valine-d9 hydrochloride

3-Methyl-L-valine-d9 hydrochloride is a deuterated derivative of 3-Methyl-L-valine hydrochloride, a non-proteinogenic amino acid. This chemical compound is used in the synthesis of peptides and proteins for research purposes, particularly in the study of protein structure and function. The deuterium substitution in 3-Methyl-L-valine-d9 hydrochloride enhances the sensitivity and resolution of mass spectrometry-based analyses. This is due to the isotopic effect, where the mass-to-charge ratio of the deuterated compound is slightly higher than the non-deuterated form. This allows for more accurate determination of the amino acid sequence and post-translational modifications of proteins. Chemically, 3-Methyl-L-valine-d9 hydrochloride is a white to off-white crystalline powder with a molecular weight of 202.76 g/mol. It is soluble in water and other polar solvents. The compound is stable under normal conditions and should be stored in a dry place at room temperature. In conclusion, 3-Methyl-L-valine-d9 hydrochloride is a useful tool in protein research due to its isotopic labeling properties. Its chemical and physical properties make it a viable option for peptide synthesis and mass spectrometry-based analysis.