3ß,5a-Tetrahydronorethisterone D5

3ß,5a-Tetrahydronorethisterone D5, also known as 3ß,5a-THNET D5, is a synthetic hormone that belongs to the group of progestins. It is commonly used as a reference standard in the analysis of progestin levels in biological samples. The "D5" in its name refers to the presence of five deuterium atoms in its chemical structure, which is useful for distinguishing it from other compounds in mass spectrometry analysis. Chemically, 3ß,5a-THNET D5 is a derivative of norethindrone, a progestin hormone commonly used in oral contraceptives. It is a white crystalline powder that is soluble in organic solvents such as ethanol and methanol. It has a molecular weight of 318.5 g/mol and a melting point of 204-206°C. In terms of usage, 3ß,5a-THNET D5 is primarily used in laboratory settings for the analysis of progestin levels in biological samples such as blood, urine, and saliva. It is often used as an internal standard in gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods for the quantification of progestins. It is also used in research to study the metabolism and pharmacokinetics of progestins. Overall, 3ß,5a-THNET D5 is a valuable tool for researchers and clinicians in the analysis and study of progestin hormones.