4-Desmethoxy-4-bromo Trimethoprim-d3
| Product Name | 4-Desmethoxy-4-bromo Trimethoprim-d3 |
|---|---|
| Alternate Names | Trimethoprim Stable Isotopes, Stable Isotopes of Trimethoprim |
| CAT No. | CS-T-73697 |
| CAS No. | 1346600-27-8 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Trimethoprim |
| Smileys | COC1=C(OC([2H])([2H])[2H])C(Br)=CC(CC2=CN=C(N)N=C2N)=C1 |
| Canonical Smiles | COC1=C(C(=CC(=C1)CC2=CN=C(N=C2N)N)Br)OC |
| InchIKey | XJSNBPJINGRLAM-BMSJAHLVSA-N |
| Inchl | InChI=1S/C13H15BrN4O2/c1-19-10-5-7(4-9(14)11(10)20-2)3-8-6-17-13(16)18-12(8)15/h4-6H,3H2,1-2H3,(H4,15,16,17,18)/i2D3 |
| IUPAC | 5-[[3-bromo-5-methoxy-4-(trideuteriomethoxy)phenyl]methyl]pyrimidine-2,4-diamine |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
4-Desmethoxy-4-bromo Trimethoprim-d3 is a deuterium-labeled derivative of Trimethoprim, which is a synthetic antibacterial drug used for treating urinary tract infections, acute otitis media, and other bacterial infections. The compound works by inhibiting the bacterial enzyme dihydrofolate reductase, which is necessary for the production of DNA, RNA, and proteins in bacteria.
The deuterium-labeled derivative, 4-Desmethoxy-4-bromo Trimethoprim-d3, is commonly used as a reference standard in pharmacokinetic studies to determine the metabolic fate of Trimethoprim in the human body. It is also used in clinical research to evaluate the efficacy and safety of Trimethoprim in different populations.
The chemical formula of 4-Desmethoxy-4-bromo Trimethoprim-d3 is C14H13BrN4O3D3, and its molecular weight is 366.26 g/mol. The compound has a melting point of 208-210°C and is soluble in water, ethanol, and dimethyl sulfoxide.
The pharmacokinetics of Trimethoprim and its deuterium-labeled derivatives have been extensively studied to understand their absorption, distribution, metabolism, and excretion in the body. These studies have provided valuable insights into the pharmacodynamics and safety of Trimethoprim, and have helped in the development of new antibacterial drugs with improved efficacy and fewer adverse effects.
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Related Compounds
Trimethoprim D3 | Trimethoprim-D9 | Trimethoprim-13C3 |