4-Hydroxy Benzeneacetic Acid 2-(Dimethylamino-d6)-2-oxoethyl Ester

4-Hydroxy Benzeneacetic Acid 2-(Dimethylamino-d6)-2-oxoethyl Ester, also known as DMOE-HABA, is a chemical compound used in biochemistry and molecular biology for the quantification of primary amines. It is a derivative of 4-hydroxybenzoic acid and contains a dimethylamino group and an ethyl ester group. The deuterium-labeled compound, DMOE-HABA-d6, is used for mass spectrometry-based analysis of protein-ligand interactions. DMOE-HABA is commonly used in the biotechnology industry as a reagent for the determination of primary amines in peptides and proteins. Its chemical structure allows it to react with primary amines to form stable, colored complexes that can be quantitatively measured. This method is used to determine the concentration of primary amines in proteins, which is essential for the characterization and quality control of protein-based drugs. In addition to its use in protein analysis, DMOE-HABA has also been used as a catalyst in organic synthesis, specifically in the preparation of chiral esters and lactones. The compound’s unique structure and reactivity make it a versatile tool in the field of chemistry. While DMOE-HABA is considered safe for use in laboratory settings, it should be handled with care to avoid skin and eye irritation. It is also important to note that the compound is not intended for human consumption and should be used only in accordance with proper safety protocols and guidelines.