5-(Methyl-d3)tetrahydrofolic acid

5-(Methyl-d3)tetrahydrofolic acid, also known as 5-Methyl-tetrahydrofolate or 5-MTHF, is a stable isotopic form of the active form of folic acid. Folic acid plays an essential role in the synthesis of DNA, RNA, and proteins, and is essential for proper cell division and growth. 5-MTHF is the biologically active form of folic acid and is required for a variety of physiological processes, including methylation reactions, neurotransmitter synthesis, and red blood cell formation. The use of 5-(Methyl-d3)tetrahydrofolic acid has been investigated in several areas of medicine. It has been found to be effective in the treatment of megaloblastic anemia, a condition characterized by the production of abnormally large red blood cells, as well as in the prevention of birth defects such as neural tube defects. It has also been studied for its potential use in the treatment of depression, cardiovascular disease, and cancer. The chemical structure of 5-(Methyl-d3)tetrahydrofolic acid is similar to that of folic acid, with the addition of deuterium atoms to the methyl group. Deuterium is a stable isotope of hydrogen that has a slightly higher atomic mass, making it useful in studies of metabolic pathways and drug metabolism. The addition of deuterium to the methyl group of 5-MTHF allows for the precise measurement of its uptake, distribution, and elimination in the body. In summary, 5-(Methyl-d3)tetrahydrofolic acid is a stable isotopic form of the biologically active form of folic acid that has been studied for its potential use in the treatment of several medical conditions. Its chemical structure allows for precise measurement of its metabolic pathways and drug metabolism, making it a useful tool in medical research.