5-Hydroxy Rosiglitazone D4
| Product Name | 5-Hydroxy Rosiglitazone D4 |
|---|---|
| Alternate Names | Rosiglitazone Stable Isotopes, Stable Isotopes of Rosiglitazone |
| CAT No. | CS-T-56453 |
| CAS No. | 1246817-46-8 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 377.45 g/mol |
| Mol. For. | C₁₈H₁₅D₄N₃O₄S |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Rosiglitazone |
| Therapeutic | Anti-Diabetic |
| Smileys | OC1=CC=C(N(C)C([2H])([2H])C([2H])([2H])OC2=CC=C(CC3C(NC(S3)=O)=O)C=C2)N=C1 |
| Canonical Smiles | CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=NC=C(C=C3)O |
| InchIKey | AGQGGZNSVNKGDU-LZMSFWOYSA-N |
| Inchl | InChI=1S/C18H19N3O4S/c1-21(16-7-4-13(22)11-19-16)8-9-25-14-5-2-12(3-6-14)10-15-17(23)20-18(24)26-15/h2-7,11,15,22H,8-10H2,1H3,(H,20,23,24)/i8D2,9D2 |
| IUPAC | 5-[[4-[1,1,2,2-tetradeuterio-2-[(5-hydroxypyridin-2-yl)-methylamino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
5-Hydroxy Rosiglitazone D4 is a synthetic drug that is primarily used in clinical research studies to investigate the pharmacokinetics and metabolic pathways of Rosiglitazone, which is an anti-diabetic medication. This compound is a deuterated derivative of Rosiglitazone, which means that it contains four hydrogen atoms that have been replaced with deuterium atoms. This modification is done to improve the accuracy and sensitivity of analytical methods used for drug analysis.
Chemically, 5-Hydroxy Rosiglitazone D4 is a thiazolidinedione derivative that works by activating peroxisome proliferator-activated receptor-gamma (PPAR-gamma), which is a nuclear receptor that regulates glucose and lipid metabolism. PPAR-gamma activation increases insulin sensitivity and glucose uptake in adipose tissue, skeletal muscle, and liver, resulting in improved glycemic control.
In addition to its use in research studies, 5-Hydroxy Rosiglitazone D4 may have potential therapeutic applications in the treatment of type 2 diabetes mellitus. However, due to the limited clinical data available, its safety and efficacy in humans are not yet established.
Overall, 5-Hydroxy Rosiglitazone D4 is a valuable tool for researchers and scientists who are working to understand the mechanisms of action and metabolism of Rosiglitazone, as well as its potential therapeutic applications in the treatment of diabetes.
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Related Compounds
Rosiglitazone D3 | Rosiglitazone D4 |