8-Hydroxy Entecavir
| Product Name | 8-Hydroxy Entecavir |
|---|---|
| Alternate Names | Entecavir Impurities, Impurities of Entecavir |
| CAT No. | CS-O-16045 |
| CAS No. | Not Available |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 293.28 g/mol |
| Mol. For. | C₁₂H₁₅N₅O₄ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Entecavir |
| Purity | Not less than 90 % |
| Therapeutic | Antiretroviral / Anti-HIV |
| Smileys | C=C([C@@H]1CO)[C@H](C[C@@H]1O)N2C(NC(N)=NC3=O)=C3NC2=O |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
8-Hydroxy Entecavir is a chemical compound that is used in the treatment of chronic hepatitis B virus infection. It is a derivative of Entecavir, which is an antiviral medication that inhibits the replication of the virus. The addition of a hydroxyl group to the molecule increases its potency and allows for a lower dose to be administered.
The chemical name of 8-Hydroxy Entecavir is 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one. It has a molecular formula of C14H17N5O4 and a molecular weight of 323.32 g/mol.
8-Hydroxy Entecavir works by inhibiting the reverse transcriptase enzyme of the hepatitis B virus, which is responsible for the replication of the virus. By blocking this enzyme, the virus is unable to reproduce and spread throughout the body. This leads to a decrease in viral load and an improvement in liver function.
The recommended dosage of 8-Hydroxy Entecavir is 0.5 mg once daily for patients with normal renal function. It is administered orally and can be taken with or without food. Patients with impaired renal function may require a lower dose or a different dosing schedule.
Overall, 8-Hydroxy Entecavir is a potent antiviral medication that is used to treat chronic hepatitis B virus infection. Its chemical structure and mechanism of action make it an effective treatment option for patients with this condition.
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Related Compounds
Entecavir EP Impurity F | Entecavir Impurity 5 | Entecavir impurity B | Entecavir Impurity 2 | Entecavir Impurity 6 (ent-Entecavir-di-O-benzyl Ether) | Entecavir Lactose Adduct Impurity 1 |