Abemaciclib D10

Product Name Abemaciclib D10
Alternate Names Abemaciclib Stable Isotopes, Stable Isotopes of Abemaciclib
CAT No. CS-O-32773
CAS No. 1231929-97-7 (Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 516.66 g/mol
Mol. For. C27H22D10F2N8
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Abemaciclib
Therapeutic Anti-Cancer / Oncology
Canonical Smiles CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F
InchIKey UZWDCWONPYILKI-UHFFFAOYSA-N
Inchl InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34)
IUPAC N-[5-[(4-ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine
Controlled No
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What is the usage and chemical information of Abemaciclib D10 ?


Abemaciclib D10 is a chemical compound that is used in the treatment of cancer. It is a potent and selective inhibitor of CDK4 and CDK6, which are enzymes that play a crucial role in cell division and proliferation. By inhibiting CDK4 and CDK6, Abemaciclib D10 prevents cancer cells from dividing and multiplying, thereby slowing down the growth and spread of cancer. Abemaciclib D10 is typically administered orally in the form of tablets. The recommended dosage and duration of treatment vary depending on the type and stage of cancer being treated, as well as the patient's overall health and medical history. It is usually prescribed by a healthcare professional who specializes in cancer treatment. In terms of chemical information, Abemaciclib D10 is a deuterated version of Abemaciclib, which means that some of its hydrogen atoms have been replaced with deuterium atoms. This modification does not affect the drug's efficacy but can improve its pharmacokinetic properties, such as absorption and distribution in the body. Like all medications, Abemaciclib D10 may cause side effects. Common side effects include fatigue, diarrhea, nausea, decreased appetite, and infections. Patients should inform their healthcare provider if they experience any adverse effects while taking this medication. In conclusion, Abemaciclib D10 is an important cancer treatment that works by inhibiting CDK4 and CDK6. It is typically administered orally and may cause side effects. Patients should follow their healthcare provider's instructions and report any adverse effects.

Related Compounds

Abemaciclib D7 | Abemaciclib D5 | Abemaciclib Impurity 5 D5 | Abemaciclib Impurity 1 D12 | Abemaciclib D8 | Abemaciclib Impurity 1 D5 |

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