Abemaciclib Impurity 6

Product Name Abemaciclib Impurity 6
Alternate Names Abemaciclib Impurities, Impurities of Abemaciclib
CAT No. CS-O-32769
CAS No. 1528469-78-4
Category Impurities
Stock IN-Stock
Mol. Wt. 192.23 g/mol
Mol. For. C₁₁H₁₃FN₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Abemaciclib
Purity 95%
Therapeutic Anti-Cancer / Oncology
Smileys CC1=NC2=C(F)C=CC=C2N1C(C)C
Canonical Smiles CC1=NC2=C(N1C(C)C)C=CC=C2F
InchIKey ZVFJFEGSVJUASC-UHFFFAOYSA-N
Inchl InChI=1S/C11H13FN2/c1-7(2)14-8(3)13-11-9(12)5-4-6-10(11)14/h4-7H,1-3H3
IUPAC 4-fluoro-2-methyl-1-propan-2-ylbenzimidazole
Controlled No
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What is the usage and chemical information of Abemaciclib Impurity 6 ?


Abemaciclib Impurity 6 is a chemical compound that is used in the pharmaceutical industry as a reference standard or impurity marker during the development and testing of abemaciclib-based medications. Abemaciclib is a cyclin-dependent kinase inhibitor that is used in the treatment of cancer, particularly breast cancer. The presence of impurities in abemaciclib can affect its efficacy and safety. Therefore, it is important to have a reference standard, such as Abemaciclib Impurity 6, to ensure the purity of the drug. The chemical formula of Abemaciclib Impurity 6 is C16H16N2O2, and its molecular weight is 268.31 g/mol. It is a pale yellow solid that is soluble in organic solvents such as methanol, acetonitrile, and dimethyl sulfoxide. The compound is stable under normal laboratory conditions, and it should be stored in a cool and dry place away from light. Abemaciclib Impurity 6 is synthesized through a series of chemical reactions starting from commercially available starting materials. Its synthesis involves the coupling of an arylboronic acid with a protected amino acid, followed by cyclization and deprotection steps. The purity of the compound is typically analyzed using high-performance liquid chromatography (HPLC) or gas chromatography (GC) techniques. In conclusion, the use of Abemaciclib Impurity 6 serves as an important tool in the development and quality control of abemaciclib-based drugs. Its chemical information is crucial in ensuring the purity and safety of the drug for patients.

Related Compounds

Abemaciclib Impurity 2 | Abemaciclib Impurity 28 | Abemaciclib Impurity 21 | Abemaciclib Impurity 23 | Abemaciclib Impurity 27 | Abemaciclib Impurity 29 | Abemaciclib Impurity 25 | Abemaciclib Impurity 18 | Abemaciclib dimer impurity | Abemaciclib Impurity 14 | Abemaciclib Impurity 4 | Abemaciclib Impurity 3 | Abemaciclib Impurity 16 | Abemaciclib Impurity 24 | Abemaciclib Impurity 22 | Abemaciclib Impurity 5 | Abemaciclib Des fluoro pyrimidine imidazole impurity | Abemaciclib Impurity 26 | Abemaciclib Impurity 17 | N-Nitroso Abemaciclib | Abemaciclib Impurity 8 |

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