Aliskiren D6 hemifumarate

Product Name Aliskiren D6 hemifumarate
Alternate Names Aliskiren Stable Isotopes, Stable Isotopes of Aliskiren
CAT No. CS-O-02668
CAS No. 173334-58-2
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 1231.66 g/mol
Mol. For. C₆₄H₉₈D₁₂N₆O₁₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Aliskiren
Purity 99.77
Therapeutic Anti-Hypertensives
Smileys OC(/C=C/C(O)=O)=O.COC1=C(C=C(C[C@H](C(C)C)C[C@H](N)[C@@H](O)C[C@@H](C(C([2H])([2H])[2H])C([2H])([2H])[2H])C(NCC(C)(C)C(N)=O)=O)C=C1)OCCCOC.CC(C)[C@H](C[C@H](N)[C@@H](O)C[C@@H](C(C)C)C(NCC(C)(C)C(N)=O)=O)CC2=CC(OCCCOC([2H])([2H])[2H])=C(C=C2)OC([2H])([2H])匀䰀开匀
Canonical Smiles CC(C)C(CC1=CC(=C(C=C1)OC)OCCCOC)CC(C(CC(C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.CC(C)C(CC1=CC(=C(C=C1)OC)OCCCOC)CC(C(CC(C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=CC(=O)O)C(=O)O
InchIKey KLRSDBSKUSSCGU-KRQUFFFQSA-N
Inchl InChI=1S/2C30H53N3O6.C4H4O4/c2*1-19(2)22(14-21-10-11-26(38-8)27(15-21)39-13-9-12-37-7)16-24(31)25(34)17-23(20(3)4)28(35)33-18-30(5,6)29(32)36;5-3(6)1-2-4(7)8/h2*10-11,15,19-20,22-25,34H,9,12-14,16-18,31H2,1-8H3,(H2,32,36)(H,33,35);1-2H,(H,5,6)(H,7,8)/b;;2-1+/t2*22-,23-,24-,25-;/m00./s1
IUPAC (2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide;(E)-but-2-enedioic acid
Controlled No
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Aliskiren D6 hemifumarate is a chemical compound that is primarily used to treat hypertension, or high blood pressure. It is an oral medication that works by inhibiting the activity of an enzyme called renin, which is involved in the production of a hormone called angiotensin II. Angiotensin II has a variety of effects on the body, including constricting blood vessels and increasing the retention of salt and water, both of which can contribute to hypertension. Aliskiren D6 hemifumarate is a deuterated form of aliskiren hemifumarate, which means that it contains six deuterium atoms instead of the normal hydrogen atoms. Deuterium is a stable isotope of hydrogen that behaves similarly to hydrogen in chemical reactions, but has a slightly different mass. This can lead to differences in the way that deuterated compounds are metabolized and eliminated from the body, which can affect their efficacy and safety. Aliskiren D6 hemifumarate is a white to off-white powder that is soluble in water and ethanol. Its chemical formula is C30H53D6N6O6.C4H4O4, and its molecular weight is 747.96 g/mol. The compound is typically administered orally in tablet form, and the recommended dosage varies depending on the patient's age, weight, and other factors. Common side effects of aliskiren D6 hemifumarate include dizziness, headache, diarrhea, and fatigue. It may also interact with other medications, so patients should inform their healthcare provider of all drugs they are taking before starting treatment with this compound.

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