all-trans-Retinoic Acid-d5 Ethyl Ester

All-trans-Retinoic Acid-d5 Ethyl Ester is a stable, isotopically labeled analog of all-trans-retinoic acid (ATRA) that is commonly used in biochemical research. ATRA is a naturally occurring derivative of vitamin A that plays a critical role in a wide range of physiological processes, including embryonic development, vision, and immune function. As a result, ATRA and its derivatives have been extensively studied for their potential therapeutic applications in various diseases, including cancer. All-trans-Retinoic Acid-d5 Ethyl Ester is particularly useful in studies of ATRA metabolism and pharmacokinetics, as its deuterium-labeled ethyl ester group allows for precise tracking and quantification of the compound in biological samples using mass spectrometry. This enables researchers to better understand how ATRA is absorbed, distributed, metabolized, and eliminated in the body, as well as how these processes might be modulated to optimize therapeutic outcomes. In addition to its research applications, All-trans-Retinoic Acid-d5 Ethyl Ester has potential clinical uses as a prodrug for ATRA delivery. The ethyl ester group can protect the ATRA molecule from degradation in the digestive tract, allowing for more efficient and targeted delivery to tissues of interest. Moreover, the deuterium-labeled ethyl ester group may confer additional benefits, such as increased stability, reduced toxicity, and improved pharmacokinetics. Overall, All-trans-Retinoic Acid-d5 Ethyl Ester represents a valuable tool for advancing our understanding of ATRA biology and developing novel therapeutic strategies.