Amphotericin B EP Impurity A

Product Name Amphotericin B EP Impurity A
Alternate Names Amphotericin B Impurities, Impurities of Amphotericin B
CAT No. CS-O-13556
CAS No. 1405-32-9
Category Impurities
Stock In stock
Mol. Wt. 926.10 g/mol
Mol. For. C₄₇H₇₅NO₁₇
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Amphotericin B
Therapeutic Anti-Fungals
Smileys OC([C@H]1[C@@](C[C@H](/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC2=O)O[C@@](O[C@H](C)[C@@H](O)[C@@H]3N)([H])[C@H]3O)([H])O[C@](O)(C[C@H](C[C@H]([C@@H](CC[C@H](C[C@H](C2)O)O)O)O)O)C[C@@H]1O)=O
Canonical Smiles CC1C=CC=CCCC=CC=CC=CC=CC(CC2C(C(CC(O2)(CC(CC(C(CCC(CC(CC(=O)OC(C(C1O)C)C)O)O)O)O)O)O)O)C(=O)O)OC3C(C(C(C(O3)C)O)N)O
InchIKey QGGFZZLFKABGNL-MOISJGEISA-N
Inchl InChI=1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
IUPAC (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
Controlled No
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What is the usage and chemical information of Amphotericin B EP Impurity A ?


Amphotericin B EP Impurity A is a chemical compound that is commonly used in the pharmaceutical industry. It is used as a reference standard in the analysis of Amphotericin B, a polyene antifungal drug used to treat various fungal infections. This impurity is a degradation product of Amphotericin B and is identified as 2-deoxy-2-[(1R, 3S, 5R, 8S, 9S, 10S, 11R, 13R, 14S, 17R)-3, 6, 8, 10, 14, 17-hexamethyl-1, 2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 13, 14, 15, 16, 17-hexadecahydrocyclopenta[a]phenanthren-17-yl]-4-methyl-pentanoic acid. Amphotericin B EP Impurity A is commonly used in the development and validation of analytical methods for the quantification of Amphotericin B in various dosage forms. It is also used in the quality control of Amphotericin B raw materials and finished products. The chemical properties of this impurity include a molecular weight of 684.99 g/mol and a melting point of 216-218°C. In conclusion, Amphotericin B EP Impurity A is an important reference standard used in the pharmaceutical industry for the analysis of Amphotericin B. Its unique chemical properties make it an ideal tool for quality control and analytical method development.

Related Compounds

Amphotericin B EP Impurity C | Amphotericin B Impurity E | Amphotericin B EP Impurity B | Amphotericin B (16s)dimethyl pentahydroxyhexyl Impurity |

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