Avanafil D4

Product Name Avanafil D4
Alternate Names Avanafil Stable Isotopes, Stable Isotopes of Avanafil
CAT No. CS-B-00233
CAS No. 330784-47-9 (Unlabelled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. 487.97 g/mol
Mol. For. C23H22D4ClN7O3
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Avanafil
Therapeutic Erectile dysfunction
Canonical Smiles COC1=C(C=C(C=C1)CNC2=NC(=NC=C2C(=O)NCC3=NC=CC=N3)N4CCCC4CO)Cl
InchIKey WEAJZXNPAWBCOA-INIZCTEOSA-N
Inchl InChI=1S/C23H26ClN7O3/c1-34-19-6-5-15(10-18(19)24)11-27-21-17(22(33)28-13-20-25-7-3-8-26-20)12-29-23(30-21)31-9-2-4-16(31)14-32/h3,5-8,10,12,16,32H,2,4,9,11,13-14H2,1H3,(H,28,33)(H,27,29,30)/t16-/m0/s1
IUPAC 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
Controlled No
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Avanafil D4 is a highly potent and selective phosphodiesterase type 5 (PDE5) inhibitor. It is a deuterated form of avanafil, which is a medication used for the treatment of erectile dysfunction (ED). Avanafil D4 works by inhibiting the breakdown of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum tissue of the penis, which leads to increased blood flow and improved erectile function. Avanafil D4 is typically administered orally in tablet form, with a recommended dosage of 100mg taken approximately 30 minutes before sexual activity. The drug has a rapid onset of action and a relatively short half-life of around 6 hours, which means it can be effective for up to 4 hours after administration. In terms of chemical information, Avanafil D4 has a molecular formula of C23H16D4N6O3 and a molecular weight of 448.52 g/mol. It is a deuterated form of avanafil, with four deuterium atoms replacing four hydrogen atoms in the molecule. Avanafil D4 has been shown to be well-tolerated in clinical studies, with common side effects including headache, flushing, and nasal congestion. It is important to note that the drug should not be used by individuals taking nitrates or alpha-blockers, as this can lead to potentially dangerous drops in blood pressure. Overall, Avanafil D4 is a promising treatment option for men with ED, offering a fast-acting and effective solution to improve sexual function.

Related Compounds

Avanafil 13C5 15N D2 | Avanafil-13C-d3 | Avanafil-13C d5 | Avanafil 13C5 | Avanafil-d5 | Avanafil 13C5 15N |

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