Axitinib 13C D3

Product Name Axitinib 13C D3
Alternate Names Axitinib Stable Isotopes, Stable Isotopes of Axitinib
CAT No. CS-O-11922
CAS No. 1261432-00-1
Category Stable Isotopes
Stock In stock
Mol. Wt. 390.48 g/mol
Mol. For. C₂₁¹³CH₁₅D₃N₄OS
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Axitinib
Purity Not less than 95 %
Therapeutic Anti-Cancer / Oncology
Smileys O=C(N[13C]([2H])([2H])[2H])C1=C(C=CC=C1)SC2=CC=C3C(/C=C/C4=CC=CC=N4)=NNC3=C2
Canonical Smiles CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)C=CC4=CC=CC=N4
Inchl InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+
IUPAC N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
Controlled No
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What is the usage and chemical information of Axitinib 13C D3 ?

Axitinib 13C D3 is a stable isotope-labelled version of the cancer drug Axitinib. Axitinib is a small molecule tyrosine kinase inhibitor that is used in the treatment of advanced renal cell carcinoma (RCC), a type of kidney cancer. Axitinib works by blocking the activity of vascular endothelial growth factor (VEGF) receptors, which are involved in the formation of new blood vessels that tumors need to grow and spread. Axitinib 13C D3 is used in clinical research studies to study the pharmacokinetics and metabolism of Axitinib in the human body. The stable isotopes of carbon and deuterium in Axitinib 13C D3 allow researchers to track the drug's movement and transformation in the body, providing important information about the drug's efficacy and safety. Chemically, Axitinib 13C D3 has the same molecular formula as Axitinib (C22H18N4OS), but contains three carbon atoms and three deuterium atoms that have been substituted with their stable isotopes. Axitinib 13C D3 is a white to off-white powder that is soluble in organic solvents such as methanol and dimethyl sulfoxide (DMSO). Overall, Axitinib 13C D3 is a valuable tool for researchers studying the pharmacokinetics and metabolism of Axitinib, and may ultimately lead to the development of more effective and safer cancer treatments.

Related Compounds

Axitinib-D3 Hydrate | Axitinib D3 |

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