Carboxyterfenadine-D3

Product Name Carboxyterfenadine-D3
CAT No. CS-BU-00030
CAS No. 83799-24-0 (unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 501.66 g/mol
Mol. For. C32H39NO4
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys OC(C1=CC=CC=C1)(C2=CC=CC=C2)C3CCN(CC([2H])([2H])C([2H])C(C4=CC=C(C(C)(C)C(O)=O)C=C4)O)CC3
Canonical Smiles CC(C)(C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O)C(=O)O
InchIKey RWTNPBWLLIMQHL-UHFFFAOYSA-N
Inchl InChI=1S/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)
IUPAC 2-[4-[1-hydroxy-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butyl]phenyl]-2-methylpropanoic acid
Controlled No
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Carboxyterfenadine-D3 is a deuterated form of Carboxyterfenadine, which is an active metabolite of Terfenadine, a second-generation antihistaminic drug. Carboxyterfenadine-D3 is an isotopically labeled compound that is widely used in pharmacological studies to investigate the metabolism and pharmacokinetics of Terfenadine and its metabolites. Chemically, Carboxyterfenadine-D3 is a carboxylic acid derivative of Terfenadine-D3, with a molecular weight of 362.5 g/mol. It is a white to off-white powder that is soluble in organic solvents such as methanol and acetonitrile. Carboxyterfenadine-D3 is primarily used as a reference standard in analytical methods such as liquid chromatography-tandem mass spectrometry (LC-MS/MS) to quantify the concentrations of Terfenadine and its metabolites in biological fluids such as plasma, urine, and saliva. It is also used in vitro to study the pharmacodynamics and pharmacokinetics of Terfenadine and its metabolites in different cell cultures and animal models. In conclusion, Carboxyterfenadine-D3 is a valuable tool for researchers studying the metabolism and pharmacological properties of Terfenadine and its active metabolites. Its isotopic labeling provides a unique advantage in analytical methods to accurately quantify the concentrations of these compounds in biological matrices.

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