Cetrorelix Impurity 22

Cetrorelix Impurity 22 is a chemical compound that is used in the pharmaceutical industry as a reference standard for the analysis of cetrorelix. Cetrorelix is a synthetic peptide hormone that is used to treat hormone-dependent diseases such as prostate cancer and endometriosis. The presence of impurities in cetrorelix can affect its efficacy and safety, which is why it is important to have reference standards for their analysis. Cetrorelix Impurity 22 is also known as des-Gly10-cetrorelix or des-Gly10-[D-Trp6]-LH-RH. It is a peptide that contains 9 amino acids and has a molecular weight of 1173.3 g/mol. It is structurally similar to cetrorelix but lacks the glycine residue at position 10. It is primarily used as a reference standard for the analysis of cetrorelix impurities by high-performance liquid chromatography (HPLC) and mass spectrometry (MS). The chemical properties of Cetrorelix Impurity 22 include a solubility in water of approximately 1 mg/mL and a melting point of around 220-230 °C. It is stable under normal storage conditions and should be stored at room temperature in a dry and dark place. It is important to handle this compound with care as it may cause skin and eye irritation. In conclusion, Cetrorelix Impurity 22 is a valuable reference standard used in the pharmaceutical industry for the analysis of cetrorelix impurities. Its chemical properties and usage make it an important tool in ensuring the safety and efficacy of cetrorelix-based treatments.