Clevidipine metabolite 13CD3

Clevidipine is a medication that is used to lower blood pressure in patients who are in critical care or undergoing surgery. It works by blocking the calcium channels in the smooth muscle cells of blood vessels, which allows the vessels to relax and widen. This results in decreased blood pressure and increased blood flow to vital organs. One of the metabolites of Clevidipine is 13CD3. This metabolite is created when the drug is broken down in the liver. It contains three deuterium atoms, which are isotopes of hydrogen that have an extra neutron in their nucleus. This gives 13CD3 slightly different chemical properties than the non-deuterated form of the metabolite. Studies have shown that 13CD3 is rapidly eliminated from the body, with a half-life of about 5 minutes. It is excreted primarily in the urine, with small amounts also found in the feces. There is limited information available on the specific effects of 13CD3, but it is believed to have similar pharmacological properties as Clevidipine. Overall, the use of Clevidipine and its metabolites, including 13CD3, can be an effective way to manage blood pressure in critically ill patients. However, it is important to monitor patients closely for any adverse reactions or interactions with other medications.