Cobicistat D8

Product Name Cobicistat D8
Alternate Names Cobicistat Stable Isotopes, Stable Isotopes of Cobicistat
CAT No. CS-O-06504
CAS No. 1004316-88-4(Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 784.07 g/mol
Mol. For. C₄₀H₄₅D₈N₇O₅S₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Cobicistat
Purity Not less than 90 %
Therapeutic Synthetic Peptides
Smileys O=C([C@@H](NC(N(C)CC1=CSC(C(C)C)=N1)=O)CCN2C([2H])([2H])C([2H])([2H])OC([2H])([2H])C2([2H])[2H])N[C@H](CC[C@@H](NC(OCC3=CN=CS3)=O)CC4=CC=CC=C4)CC5=CC=CC=C5
Canonical Smiles CC(C)C1=NC(=CS1)CN(C)C(=O)NC(CCN2CCOCC2)C(=O)NC(CCC(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)CC5=CC=CC=C5
InchIKey ZCIGNRJZKPOIKD-CQXVEOKZSA-N
Inchl InChI=1S/C40H53N7O5S2/c1-29(2)38-43-34(27-53-38)25-46(3)39(49)45-36(16-17-47-18-20-51-21-19-47)37(48)42-32(22-30-10-6-4-7-11-30)14-15-33(23-31-12-8-5-9-13-31)44-40(50)52-26-35-24-41-28-54-35/h4-13,24,27-29,32-33,36H,14-23,25-26H2,1-3H3,(H,42,48)(H,44,50)(H,45,49)/t32-,33-,36+/m1/s1
IUPAC 1,3-thiazol-5-ylmethyl N-[(2R,5R)-5-[[(2S)-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]-4-morpholin-4-ylbutanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate
Controlled No
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Cobicistat D8 is a deuterated form of Cobicistat, a medication used in the treatment of HIV-1 infection. It is a potent inhibitor of the enzyme cytochrome P450 3A (CYP3A), which is involved in the metabolism of many drugs, including those used to treat HIV. By inhibiting CYP3A, Cobicistat D8 increases the concentrations of other drugs in the body, allowing for lower doses and fewer side effects. Cobicistat D8 is typically used in combination with other antiretroviral drugs to treat HIV-1 infection in adults. It is taken orally, once daily, with or without food. Like other antiretroviral drugs, Cobicistat D8 does not cure HIV, but it can help to control the virus and prevent the progression of AIDS. Chemically, Cobicistat D8 is a deuterated analog of Cobicistat, which means that it contains eight deuterium atoms instead of eight hydrogen atoms. This modification can help to improve the pharmacokinetic properties of the drug, such as its bioavailability and metabolic stability. Overall, Cobicistat D8 is an important medication in the treatment of HIV-1 infection, and its use can help to improve the quality of life for those living with the disease.

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