Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde

Product Name Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde
Alternate Names Losartan Impurities, Impurities of Losartan
CAT No. CS-T-16638
CAS No. 124750-67-0
Category Impurities
Stock In stock
Mol. Wt. 377.87 g/mol
Mol. For. C₂₂H₂₀ClN₃O
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Losartan
Therapeutic Anti-Hypertensives
Smileys N#CC1=CC=CC=C1C2=CC=C(CN3C(C=O)=C(Cl)N=C3CCCC)C=C2
Canonical Smiles CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C#N)C=O)Cl
InchIKey UYWHRPJKNDNURE-UHFFFAOYSA-N
Inchl InChI=1S/C22H20ClN3O/c1-2-3-8-21-25-22(23)20(15-27)26(21)14-16-9-11-17(12-10-16)19-7-5-4-6-18(19)13-24/h4-7,9-12,15H,2-3,8,14H2,1H3
IUPAC 2-[4-[(2-butyl-4-chloro-5-formylimidazol-1-yl)methyl]phenyl]benzonitrile
Controlled No
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What is the usage and chemical information of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde ?


Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde is a chemical compound that is primarily used as an angiotensin II receptor antagonist. It is a derivative of losartan, which is a commonly used medication for treating high blood pressure. The addition of the tetrazolyl group to the losartan molecule enhances its binding affinity to the angiotensin II receptor, making it a more potent medication. The chemical formula of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde is C22H18N6O3. It has a molecular weight of 426.41 g/mol. The compound is a yellow powder that is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol. The mechanism of action of Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde involves blocking the action of the hormone angiotensin II. This hormone is responsible for constricting blood vessels, increasing blood pressure, and stimulating the release of aldosterone, which promotes water and salt retention. By blocking the action of angiotensin II, Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde helps to relax blood vessels, lower blood pressure, and reduce the workload on the heart. In conclusion, Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan Carboxaldehyde is a potent angiotensin II receptor antagonist that is used for treating high blood pressure. Its chemical structure and mechanism of action make it a valuable medication for managing hypertension and reducing the risk of cardiovascular disease.

Related Compounds

Losartan Hydroxy N1-Trityl Impurity | Losartan Potassium EP Impurity J | Nitroso Losartan | Losartan Impurity 5 | Losartan isocyano Impurity | Losartan Potassium EP Impurity H | Losartan Imidazo[1,5-b]isoquinoline Impurity | Losartan Acetyloxy Impurity | Losartan EP Impurity F | Losartan EP Impurity B | Losartan Impurity 8 | Losartan Potassium EP Impurity E | Losartan Acetyloxy N1-Trityl Impurity | N-Trityl Losartan Isomer | N-Trityl Losartan Carboxaldehyde | Losartan Impurity 29 | Losartan N1-Trityl Impurity | Des[2-(1H-tetrazol-5-yl)] 2-Cyanolosartan | Losartan Related Compound D | Losartan Impurity 1 | Losartan Impurity 15 | Losartan EP Impurity M | Losartan Potassium EP Impurity A | Losartan Related Compound E | N-Trityl Losartan Carboxylic Acid | Losartan a-Butyl-losartan Aldehyde Adduct | Losartan Potassium EP Impurity K | Losartan Amine | Losartan EP Impurity L | Losartan Impurity 7 | Losartan Impurity 6 | Losartan EP Impurity C | Losartan Azide impurity | Losartan Potassium EP Impurity C | Losartan Dimer Azide |

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