Diltiazem D6

Product Name Diltiazem D6
Alternate Names Diltiazem Stable Isotopes, Stable Isotopes of Diltiazem
CAT No. CS-O-06546
CAS No. 1242184-41-3
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 420.55 g/mol
Mol. For. C₂₂H₂₀D₆N₂O₄S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Diltiazem
Purity 98.24
Therapeutic Anti-Migraines
Smileys CC(O[C@@H]1[C@H](C2=CC=C(OC)C=C2)SC3=CC=CC=C3N(CCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C1=O)=O
Canonical Smiles CC(=O)OC1C(SC2=CC=CC=C2N(C1=O)CCN(C)C)C3=CC=C(C=C3)OC
InchIKey HSUGRBWQSSZJOP-NFBMDBORSA-N
Inchl InChI=1S/C22H26N2O4S/c1-15(25)28-20-21(16-9-11-17(27-4)12-10-16)29-19-8-6-5-7-18(19)24(22(20)26)14-13-23(2)3/h5-12,20-21H,13-14H2,1-4H3/t20-,21+/m1/s1/i2D3,3D3
IUPAC [(2S,3S)-5-[2-[bis(trideuteriomethyl)amino]ethyl]-2-(4-methoxyphenyl)-4-oxo-2,3-dihydro-1,5-benzothiazepin-3-yl] acetate
Controlled No
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Diltiazem D6 is a deuterated form of the calcium channel blocker Diltiazem. It is commonly used in analytical research to determine the bioavailability, metabolism, and pharmacokinetics of Diltiazem in the body. Diltiazem D6 works by inhibiting the influx of calcium ions into cardiac and smooth muscle cells, leading to decreased contractility and relaxation of the blood vessels. This results in a reduction in blood pressure and increased oxygen supply to the heart. The chemical structure of Diltiazem D6 is similar to that of Diltiazem, with the exception of six deuterium atoms that are substituted for hydrogen atoms. This modification allows for more accurate and sensitive detection of the drug in biological samples, as well as a more precise understanding of its metabolic pathways and excretion. In terms of safety and side effects, Diltiazem D6 has similar properties to Diltiazem. It is generally well-tolerated, but can cause dizziness, headache, and constipation in some patients. It may also interact with other medications, so it is important to consult a healthcare provider before use. Overall, Diltiazem D6 is a valuable tool for researchers studying the pharmacology and pharmacokinetics of Diltiazem. Its deuterated structure allows for accurate measurement and analysis of the drug in biological samples, leading to a better understanding of its effects and potential applications in clinical settings.

Related Compounds

N-desmethyl N-nitroso Diltiazem-D3 | O-Desacetyl N-Desmethyl Diltiazem D3 | Desacetyl Diltiazem D6 HCl | Desacetyl Diltiazem-d6 hydrochloride | Desacetyl Diltiazem D4 | N-Desmethyl Diltiazem D4 | Desacetyl Diltiazem-d6 | Diltiazem D5 | N-Desmethyl Diltiazem-d3 Hydrochloride | Desacetyl Diltiazem-d3 | Desacetyldiltiazem-d5 HCl | Diltiazem D6 HCl | N-Desmethyldiltiazem-d5 Maleate | Diltiazem D4 | N-Desmethyl Diltiazem D4 hydrochloride | Diltiazem d4 HCl | Diltiazem-d3 Hydrochloride | Desacetyl Diltiazem D4 HCl |

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