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Dimepranol D6 is a deuterated analog of the pharmaceutical compound Dimepranol. It is a potent and selective inhibitor of dihydroorotate dehydrogenase (DHODH), an enzyme that plays a critical role in the production of pyrimidine nucleotides, which are essential building blocks of DNA and RNA.
Dimepranol D6 is commonly used in biochemical research to study the role of DHODH in various cellular processes, such as cell proliferation, differentiation, and apoptosis. It is also used as a tool compound in drug discovery programs aimed at developing new therapies for cancer, autoimmune diseases, and viral infections.
Chemically, Dimepranol D6 is a stable isotopically labeled compound that contains six deuterium atoms, which replace six hydrogen atoms in the original compound. This modification enhances the compound's stability and bioavailability, making it an ideal tool for in vivo studies.
Dimepranol D6 is typically administered in vitro as a powder or in solution form. It is highly soluble in most polar solvents, including water, ethanol, and methanol, and has a molecular weight of 267.39 g/mol.
In summary, Dimepranol D6 is a valuable research tool that is widely used to study the function of DHODH in various cellular processes. Its stable isotopic labeling and high bioavailability make it an ideal tool for in vivo studies, and its solubility in a wide range of solvents makes it easy to administer in vitro.
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