Elvitegravir 13C6

Product Name Elvitegravir 13C6
Alternate Names Elvitegravir Stable Isotopes, Stable Isotopes of Elvitegravir
CAT No. CS-EK-00215
CAS No. 697761-98-1 unlabeled
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Elvitegravir
Canonical Smiles CC(C)C(CO)N1C=C(C(=O)C2=C1C=C(C(=C2)CC3=C(C(=CC=C3)Cl)F)OC)C(=O)O
InchIKey JUZYLCPPVHEVSV-LJQANCHMSA-N
Inchl InChI=1S/C23H23ClFNO5/c1-12(2)19(11-27)26-10-16(23(29)30)22(28)15-8-14(20(31-3)9-18(15)26)7-13-5-4-6-17(24)21(13)25/h4-6,8-10,12,19,27H,7,11H2,1-3H3,(H,29,30)/t19-/m1/s1
IUPAC 6-[(3-chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-methoxy-4-oxoquinoline-3-carboxylic acid
Controlled No
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[13C6]-Elvitegravir is a stable isotope-labeled version of the antiretroviral drug Elvitegravir, which is used in the treatment of human immunodeficiency virus (HIV) infections. The stable isotope labeling of [13C6]-Elvitegravir allows for its use in pharmacokinetic studies, drug metabolism studies, and clinical trials to determine the efficacy and safety of the drug. Elvitegravir belongs to the Integrase Strand Transfer Inhibitor (INSTI) class of antiretroviral drugs, which work by inhibiting the activity of the integrase enzyme that is essential for the replication of HIV in the host cells. By blocking the activity of integrase, Elvitegravir prevents the integration of viral DNA into the host cell's genome, thereby reducing the viral load in the patient's blood. The chemical formula of [13C6]-Elvitegravir is C23H23C13N6O, and its molecular weight is 447.53 g/mol. The stable isotope labeling replaces six carbon atoms in the molecule with carbon-13 isotopes, which have a natural abundance of 1.1%. The stable isotope-labeled drug is synthesized using chemical methods that involve the incorporation of [13C6]-labeled precursors during the synthesis of the drug molecule. In conclusion, [13C6]-Elvitegravir is a useful tool for studying the pharmacokinetics, metabolism, and clinical efficacy of Elvitegravir in HIV-positive patients. Its stable isotope labeling provides a unique signature that allows for its identification and quantification in biological samples, making it an essential tool for drug development and clinical trials.

Related Compounds

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